I have been recently using context/problem based learning to deliver biological mass spectrometry to year one bioscience students. The approach has been generally well received and I plan to do a re-run this year but to a larger year one group. I reported on this at the UK Centre for Bioscience reps forum in September last year and have included the slides below.
I would be very interested to hear from colleagues who have also used this approach in teaching in the biosciences or physical sciences.